Pathogenesis of Plexiform Neurofibroma: Tumor-Stromal/Hematopoietic Interactions in Tumor Progression

plexiform neurofibroma tumor in the parapharyngeal neck space

a 4.5 years old boy with left postero superior lateral neck mass admitted to shahid rahnemoon hospital in yazd. the mass had been noticed 2 years ago and there was no improvement after three times antibiotic therapy. on physical examination there were two masses on the neck. one of them was approximately 3×4 cm and the other was 2×2 cm. on of the masses was located in the left posterior auricul...

Fast Semi-Automatic Plexiform Neurofibroma Tumor Segmentation in MRI Scans

Plexiform Neurofibroma: A Rare Tumor of Submandibular Salivary Gland

A 15-year-old boy presented with swelling in the submandibular region. X-ray of the swollen part showed faint radio opaque shadow. A provisional diagnosis of sialadenitis with sialolithiasis was made. Excised mass was reported histopathologically as plexiform neurofibroma of submandibular salivary gland.Plexiform neurofibroma of the salivary gland is a rare benign tumor often present in the par...

Plexiform neurofibroma of penis.

Received January 2006 Accepted December 2006 INTRODUCTION Neurofibromas are tumors originating from the Schwann cells in the neural sheath of the cranial, peripheral, and visceral nerves. The gross appearance of neurofibromas varies greatly in different lesions. Superficial tumors appear as small, soft, pedunculated, or sessile nodules protruding from the skin. But, deeper tumors are larger. Tu...

Tumor and Stem Cell Biology Susceptible Stages in Schwann Cells for NF1-Associated Plexiform Neurofibroma Development

Stem cells are under strict regulation by both intrinsic factors and the microenvironment. There is increasing evidence that many cancers initiate through acquisition of genetic mutations (loss of intrinsic control) in stem cells or their progenitors, followed by alterations of the surrounding microenvironment (loss of extrinsic control). In neurofibromatosis type 1 (NF1), deregulation of Ras s...